[Genetics of mental retardation].

The relation between consanguineous marriage and mental retardation of the offspring

OCCURRENCE OF REPEATED FETAL DEATHS AND A SON WITH SEVERE PHYSICAL AND MENTAL RETARDATION AMONG PROGENIES OF AN IRANIAN CHEMICAL WARFARE VICTIM

Ring Chromosome 18: A Case Report

Ring chromosomes are rare chromosomal disorders that usually appear to occur de novo. A ring chromosome forms when due to deletion both ends of chromosome fuse with each other. Depending on the amount of chromosomal deletion, the clinical manifestations may be different. So, ring 18 syndrome is characterized by severe mental growth retardation as well as microcephaly, brain and ocular malformat...

X linked mental retardation: a clinical guide.

Mental retardation is more common in males than females in the population, assumed to be due to mutations on the X chromosome. The prevalence of the 24 genes identified to date is low and less common than expansions in FMR1, which cause Fragile X syndrome. Systematic screening of all other X linked genes in X linked families with mental retardation is currently not feasible in a clinical settin...

A new X linked syndrome with mental retardation and craniofacial dysmorphism?

We present a syndrome manifested in two half brothers and their two maternal aunts which is characterised in the two boys by severe mental retardation and craniofacial dysmorphism (broad, coarse features and marked plagiocephaly with flattened occiput), and in the aunts merely by moderate mental retardation without dysmorphic features. The brothers do not seem to fall into any previously descri...

Familial mental retardation.

Familial patterns of mental retardation were examined among white and black children in the NINCDS Collaborative Perinatal Project population. Among whites, the mildly retarded children had more affected relatives than did the severely retarded, consistent with the traditional two-group theory of mental retardation. In blacks, where differences in family patterns between the mildly and the seve...